Outcome and intestinal adaptation in neonatal short-bowel syndrome.
作者： Keith E. Georgeson , Charles W. Breaux
DOI: 10.1016/0022-3468(92)90859-6
关键词: Parenteral nutrition 、 Short bowel syndrome 、 Serial transverse enteroplasty 、 Ileocecal valve 、 Medicine 、 Necrotizing enterocolitis 、 Enterocolitis 、 Gastroenterology 、 Volvulus 、 Survival rate 、 Internal medicine
摘要: We reviewed 52 consecutive patients with short-bowel syndrome (SBS) treated long-term parenteral nutrition (PN) from 1978 through 1990. The SBS etiologies included necrotizing enterocolitis (NEC) in 26 (50%), abdominal wall defects 11 (22%), jejunoileal atresia 6 (12%), midgut volvulus 4 (8%), Hirschsprung's disease 3 (6%), and segmental cloacal exstrophy 1 (2%) each. average initial small bowel length was 48.1 cm, only 31% of the retained an ileocecal valve (ICV). mean duration PN therapy 16.6 months, 39 (75%) were successfully weaned it. Forty-three (83%) survived. Significant differences between 20 1984 next 32 1985 1990 (25.1 v 11.4 months; P = .04), incidence PN-associated jaundice (80% 31%; .001), survival (65% 94%; .02). NEC had a significantly lower birthweight than those other (mean, 1,367 2,544 g; less .0001) but did not differ length, ICV retention rate, treatment, successful weaning, or outcome. presence correlate weaning affect (7.2 months 21.6 without; .03).(ABSTRACT TRUNCATED AT 250 WORDS)
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