Pregnancy during long-term gonadotropin-releasing hormone agonist therapy associated with clinical pseudomenopause

作者: Joseph Har-Toov , Steven H. Brenner , Ariel Jaffa , Haim Yavetz , M. Reuben Peyser

DOI: 10.1016/S0015-0282(16)55702-1

关键词: Ovulatory cycleFertilityPregnancyGonadotropin-releasing hormone agonistChemotherapyAgonistComplicationInternal medicineEndocrinologyRisk factorMedicine

摘要: A case of pregnancy occurring with escape suppression from GnRH-a therapy is described. Clinical pseudomenopause had been established, and the was exposed to depot for 8 weeks. Normal outcome demonstrated that successful implantation may occur in first escaped ovulatory cycle.

参考文章(6)
J. Happ, H. Schultheiß, G.H. Jacobi, U.K. Wenderoth, K. Buttenschön, K. Miesel, H. Spahn, G. Hör, Pharmacodynamics, pharmacokinetics and bioavailability of the prolonged LH-RH agonist decapeptyl-SR European Journal of Cancer and Clinical Oncology. ,vol. 22, pp. 742- ,(1986) , 10.1016/0277-5379(86)90275-0
George Tolis, Anna Maria Comaru-Schally, Adi E. Mehta, Andrew V. Schally, Failure to Interrupt Established Pregnancy in Humans by d-Tryptophan-6-Luteinizing Hormone-Releasing Hormone Fertility and Sterility. ,vol. 36, pp. 241- 242 ,(1981) , 10.1016/S0015-0282(16)45688-8
Raphael Ron-El, Abraham Golan, Arie Herman, Arie Raziel, Yigal Soffer, Eliahu Caspi, Midluteal gonadotropin-releasing hormone analog administration in early pregnancy. Fertility and Sterility. ,vol. 53, pp. 572- 574 ,(1990) , 10.1016/S0015-0282(16)53361-5
Inn Soo Kang, Thomas J. Kuehl, Theresa M. Siler-Khodr, Effect of treatment with gonadotropin-releasing hormone analogues on pregnancy outcome in the baboon Fertility and Sterility. ,vol. 52, pp. 846- 853 ,(1989) , 10.1016/S0015-0282(16)53051-9
Hammond Jm, Ghazi Dm, Kemmann E, Normal pregnancy outcome after early maternal exposure to gonadotropin releasing hormone agonist : a case report Journal of Reproductive Medicine. ,vol. 36, pp. 173- 174 ,(1991)
Abraham Golan, Raphael Ron-El, Arie Herman, Zvi Weinraub, Yigal Soffer, Eliahu Caspi, Fetal outcome following inadvertant administration of long-acting DTRP6 GnRH microcapsules during pregnancy: a case report Human Reproduction. ,vol. 5, pp. 123- 124 ,(1990) , 10.1093/OXFORDJOURNALS.HUMREP.A137031