PD-L1 expression is a favorable prognostic factor in early stage non-small cell carcinoma
作者： Wendy A. Cooper , Thang Tran , Ricardo E. Vilain , Jason Madore , Christina I. Selinger
DOI: 10.1016/J.LUNGCAN.2015.05.007
关键词: Tissue microarray 、 Carcinoma 、 Lung cancer 、 Predictive marker 、 Oncology 、 Medicine 、 Immune checkpoint 、 Stage (cooking) 、 Biomarker (medicine) 、 Internal medicine 、 Immunohistochemistry
摘要: Objectives Immune checkpoint blockade using inhibitors of programmed death-1 have shown promise in early phase clinical trials in NSCLC and programmed death-ligand 1 (PD-L1) tumoral expression could potentially be a useful predictive marker. Data reporting the prevalence of PD-L1 expression in NSCLC and clinicopathologic associations is very limited. We sought to determine the frequency of PD-L1 expression in NSCLC and investigate associations with clinicopathologic features and patient outcome. Materials and …
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