Targeting lactate metabolism for cancer therapeutics

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Hiroaki Shime, Masahiko Yabu, Takashi Akazawa, Ken Kodama, Misako Matsumoto, Tsukasa Seya, Norimitsu Inoue, Tumor-Secreted Lactic Acid Promotes IL-23/IL-17 Proinflammatory Pathway Journal of Immunology. ,vol. 180, pp. 7175- 7183 ,(2008) , 10.4049/JIMMUNOL.180.11.7175

Céline Pinheiro, André Albergaria, Joana Paredes, Bárbara Sousa, Rozany Dufloth, Daniella Vieira, Fernando Schmitt, Fátima Baltazar, Monocarboxylate transporter 1 is up-regulated in basal-like breast carcinoma Histopathology. ,vol. 56, pp. 860- 867 ,(2010) , 10.1111/J.1365-2559.2010.03560.X

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Maria Q Baggstrom, Yingwei Qi, Marianna Koczywas, Athanassios Argiris, Elizabeth A Johnson, Michael J Millward, Sara C Murphy, Charles Erlichman, Charles M Rudin, Ramaswamy Govindan, Mayo Phase 2 Consortium, California Consortium, A phase II study of AT-101 (Gossypol) in chemotherapy-sensitive recurrent extensive-stage small cell lung cancer. Journal of Thoracic Oncology. ,vol. 6, pp. 1757- 1760 ,(2011) , 10.1097/JTO.0B013E31822E2941

Kiyoshi Asada, Kazuaki Miyamoto, Takashi Fukutomi, Hitoshi Tsuda, Yukiko Yagi, Kuniko Wakazono, Shoko Oishi, Hiroshi Fukui, Takashi Sugimura, Toshikazu Ushijima, Reduced Expression of GNA11 and Silencing of MCT1 in Human Breast Cancers Oncology. ,vol. 64, pp. 380- 388 ,(2003) , 10.1159/000070297

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