Transition Metal-Free Synthesis of Carbo- and Heterocycles via Reaction of Alkynes with Organylchalcogenides.
作者： Gilson Zeni , Benhur Godoi , Carla K. Jurinic , Andrei L. Belladona , Ricardo F. Schumacher
关键词: Alkyne 、 Photoredox catalysis 、 Triple bond 、 Transition metal 、 Halide 、 Polymer chemistry 、 Radical cyclization 、 Electrophile 、 Chemistry 、 Reagent
摘要: This manuscript intends to overview the most recent advances in synthesis of carbo- and heterocycles through reactions alkynes with organyl chalcogenides (S, Se, Te) under metal-free conditions. Firstly, use electrophilic chalcogenyl halides as a selective reagent for alkyne carbon-carbon triple bond activation will be presented. After that, radical cyclization protocols employing electrochemical oxidative conditions, light-induced photoredox catalysis, or mild oxidants direct group installation discussed accompanied by proposed mechanisms.
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