Evidence-based principles in pathology: existing problem areas and the development of "quality" practice patterns.

摘要: Context.—Contrary to the intuitive impressions of many pathologists, several areas exist in laboratory medicine where evidence-based (EBM) principles are not applied. These include aspects both anatomic and clinical pathology. Some non-EBM practices perpetuated by “consumers” services because inadequate education, habit, or overreliance on empirical factors. Other faulty procedures driven pathologists themselves. Objectives.—To consider (1) selected problem representing medicine; such examples ideas techniques that concern metastatic malignancies, “targeted” oncologic therapy, general testing data utilization, evaluation coagulation defects, administration blood products, analysis hepatic iron-overload syndromes; (2) EBM as methods for remediation deficiencies hospital pathology, implements construction “quality” ou...