Changes in neurocognitive functioning following lung transplantation.

作者: B. M. Hoffman , J. A. Blumenthal , R. C. Carney , C. V. F. O’Hayer , K. Freedland

DOI: 10.1111/J.1600-6143.2012.04072.X

关键词: CognitionNeurocognitiveCystic fibrosisSurgeryRevascularizationCognitive declineLung transplantationVerbal memoryMedicineOlder patientsInternal medicine

摘要: Although neurocognitive impairment is relatively common among patients with advanced lung disease, little known regarding changes in neurocognition following transplantation. We therefore administered 10 tests of functioning before and 6 months transplantation sought to identify predictors change. Among the 49 study participants, native diseases included chronic obstructive pulmonary disease (n = 22), cystic fibrosis 12), nonfibrotic 11) other 4). composite measures executive function verbal memory scores were generally within normal limits both after transplantation, performance was slightly better posttransplant compared baseline (p 1 standard deviations on at least 20% tests) from posttransplant. Patients who declined older < 0.004) tended be less educated 0.07). Lung like cardiac revascularization procedures, appears associated cognitive decline a subset patients, which could impact daily

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