Pheochromocytoma and Paraganglioma

作者: Eleonora P. Corssmit , Leonie T. van Hulsteijn

DOI: 10.1007/978-3-662-45215-8_24

关键词: SDHBNeuroendocrine tumorsPheochromocytomaCarotid Body ParagangliomaParagangliomaSDHDPathologyAdrenalectomyRadiation therapyMedicine

摘要: Paragangliomas (PGLs) are rare vascular, neuroendocrine tumors of paraganglia. They can occur sporadically or hereditary, due to germ-line mutations in one 10 susceptibility genes. PGLs derive from either sympathetic tissue adrenal (pheochromocytomas PCCs) and extra-adrenal (sPGLs) locations parasympathetic the head neck (HNPGLs). Since HNPGLs usually benign most grow slowly, a wait-and-scan policy is often advised. However, their location close proximity nerves vasculature result considerable morbidity compression infiltration adjacent structures. The main treatment modalities for HNPGL surgery radiotherapy.

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