作者: Eleonora P. Corssmit , Leonie T. van Hulsteijn
DOI: 10.1007/978-3-662-45215-8_24
关键词: SDHB 、 Neuroendocrine tumors 、 Pheochromocytoma 、 Carotid Body Paraganglioma 、 Paraganglioma 、 SDHD 、 Pathology 、 Adrenalectomy 、 Radiation therapy 、 Medicine
摘要: Paragangliomas (PGLs) are rare vascular, neuroendocrine tumors of paraganglia. They can occur sporadically or hereditary, due to germ-line mutations in one 10 susceptibility genes. PGLs derive from either sympathetic tissue adrenal (pheochromocytomas PCCs) and extra-adrenal (sPGLs) locations parasympathetic the head neck (HNPGLs). Since HNPGLs usually benign most grow slowly, a wait-and-scan policy is often advised. However, their location close proximity nerves vasculature result considerable morbidity compression infiltration adjacent structures. The main treatment modalities for HNPGL surgery radiotherapy.