Biomarkers (Procalcitonin, C Reactive Protein, and Lactate) as Predictors of Mortality in Surgical Patients with Complicated Intra-Abdominal Infection.
作者： Alejandro Suarez-de-la-Rica , Emilio Maseda , Víctor Anillo , Eduardo Tamayo , Carlos A. García-Bernedo
DOI: 10.1089/SUR.2014.178
关键词: C-reactive protein 、 Logistic regression 、 Severity of illness 、 Intensive care medicine 、 Procalcitonin 、 Simplified Acute Physiology Score 、 Internal medicine 、 SAPS II 、 Medicine 、 Retrospective cohort study 、 Survival analysis
摘要: Abstract Background: An accurate and readily available biomarker for identifying patients with complicated intra-abdominal infection needing special attention in critical care units because of their greater risk dying would be value intensivists. Methods: A multi-center, observational, retrospective study explored blood lactate, C-reactive protein (CRP), procalcitonin (PCT) concentrations, also Sequential Organ Failure Assessment (SOFA) Simplified Acute Physiology Score (SAPS II) as mortality predictors all adult (cIAI) admitted to Surgical Critical Care Units (SCCUs) ≥48 h four Spanish hospitals (June 2012–June 2013). Logistic regression models (step-wise procedure) were constructed using dependent variables “intra-SCCU mortality” or “overall mortality,” showing differences (p≤0.1) bivariate analyses independent variables. Results: One hundred twenty-one cases included. Mortality intra-SCCU (R2...
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