How the Hedgehog Outfoxed the Crab

Alex K Wong, Lynda Chin, An inducible melanoma model implicates a role for RAS in tumor maintenance and angiogenesis. Cancer and Metastasis Reviews. ,vol. 19, pp. 121- 129 ,(2000) , 10.1023/A:1026537423753

L.R. Kelland, “Of mice and men”: values and liabilities of the athymic nude mouse model in anticancer drug development European Journal of Cancer. ,vol. 40, pp. 827- 836 ,(2004) , 10.1016/J.EJCA.2003.11.028

Lynda Chin, Alice Tam, Jason Pomerantz, Michelle Wong, Jocelyn Holash, Nabeel Bardeesy, Qiong Shen, Ronan O'Hagan, Joe Pantginis, Hao Zhou, James W. Horner, Carlos Cordon-Cardo, George D. Yancopoulos, Ronald A. DePinho#, Essential role for oncogenic Ras in tumour maintenance Nature. ,vol. 400, pp. 468- 472 ,(1999) , 10.1038/22788

J Michael Ruppert, Peggy R McKie-Bell, Lindsey S South, Ronald L Johnson, Iúri D Louro, Martin R Johnson, Xingnan Li, Conway C Huang, Bradley K Yoder, Aubrey E Hill, Evans C Bailey, Comparative Gene Expression Profile Analysis of GLI and c-MYC in an Epithelial Model of Malignant Transformation Cancer Research. ,vol. 62, pp. 5867- 5873 ,(2002)

Masateru Katayama, Kazunari Yoshida, Hisatsugu Ishimori, Makoto Katayama, Takeshi Kawase, Jun Motoyama, Hiroyuki Kamiguchi, Patched and smoothened mRNA expression in human astrocytic tumors inversely correlates with histological malignancy Journal of Neuro-oncology. ,vol. 59, pp. 107- 115 ,(2002) , 10.1023/A:1019660421216

Guido Reifenberger, Thomas Ruzicka, Marietta Wolter, Julia Reifenberger, Clemens Sommer, Mutations in the human homologue of the Drosophila segment polarity gene patched (PTCH) in sporadic basal cell carcinomas of the skin and primitive neuroectodermal tumors of the central nervous system Cancer Research. ,vol. 57, pp. 2581- 2585 ,(1997)

Ningning Miao, Monica Wang, Jennifer A. Ott, Josephine S. D’Alessandro, Tod M. Woolf, David A. Bumcrot, Nagesh K. Mahanthappa, Kevin Pang, Sonic Hedgehog Promotes the Survival of Specific CNS Neuron Populations and Protects These Cells from Toxic InsultIn Vitro The Journal of Neuroscience. ,vol. 17, pp. 5891- 5899 ,(1997) , 10.1523/JNEUROSCI.17-15-05891.1997

Corey Raffel, Benjamin Alderete, Deanne Hebrink, C. David James, Robert B. Jenkins, Daniel W. Fults, Lori Frederick, Sporadic Medulloblastomas Contain PTCH Mutations Cancer Research. ,vol. 57, pp. 842- 845 ,(1997)

Sinan Taş, Oktay Avcı, Rapid Clearance of Psoriatic Skin Lesions Induced by Topical Cyclopamine Dermatology. ,vol. 209, pp. 126- 131 ,(2004) , 10.1159/000079596

Cynthia Wetmore, Tom Curran, Derek E. Eberhart, Loss of p53 but not ARF accelerates medulloblastoma in mice heterozygous for patched. Cancer Research. ,vol. 61, pp. 513- 516 ,(2001)