Protein engineering and the use of molecular modeling and simulation: The case of heterodimeric Fc engineering

作者: Thomas Spreter Von Kreudenstein , Paula I. Lario , Surjit B. Dixit

DOI: 10.1016/J.YMETH.2013.10.016

关键词: NanotechnologyProtein engineeringEngineering programBispecific antibodyIn silicoComputer scienceMolecular modelBiochemical engineeringWorkflow

摘要: … overview of the state of the art of the field of computational modeling and simulation of protein structure and how we employ these methods as tools for heterodimeric Fc engineering. …

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