Development of Amplifi cation-Based Molecular Genetic Testing in Hematology

Daniel H. Farkas, Carol A. Holland, Overview of Molecular Diagnostic Techniques and Instrumentation Cell and Tissue Based Molecular Pathology. pp. 19- 32 ,(2009) , 10.1016/B978-044306901-7.50008-0

Adam Bagg, Chronic myeloid leukemia: a minimalistic view of post-therapeutic monitoring. The Journal of Molecular Diagnostics. ,vol. 4, pp. 1- 10 ,(2002) , 10.1016/S1525-1578(10)60675-7

Francis J. Giles, FLT3 inhibitor KRN383 on xenografted human leukemic cells harboring FLT3-activating mutations FLT3 in AML: much more to learn about biology and optimal targeting. Leukemia Research. ,vol. 30, pp. 1469- 1470 ,(2006) , 10.1016/J.LEUKRES.2006.03.002

JP Radich, G Gehly, T Gooley, E Bryant, RA Clift, S Collins, S Edmands, J Kirk, A Lee, P Kessler, Polymerase chain reaction detection of the BCR-ABL fusion transcript after allogeneic marrow transplantation for chronic myeloid leukemia: results and implications in 346 patients Blood. ,vol. 85, pp. 2632- 2638 ,(1995) , 10.1182/BLOOD.V85.9.2632.BLOODJOURNAL8592632

Ayalew Tefferi, Juergen Thiele, James W. Vardiman, The 2008 World Health Organization classification system for myeloproliferative neoplasms: order out of chaos. Cancer. ,vol. 115, pp. 3842- 3847 ,(2009) , 10.1002/CNCR.24440

Robert Kralovics, Francesco Passamonti, Andreas S. Buser, Soon-Siong Teo, Ralph Tiedt, Jakob R. Passweg, Andre Tichelli, Mario Cazzola, Radek C. Skoda, A Gain-of-Function Mutation of JAK2 in Myeloproliferative Disorders The New England Journal of Medicine. ,vol. 352, pp. 1779- 1790 ,(2005) , 10.1056/NEJMOA051113

F. M. Abu-Duhier, A. C. Goodeve, G. A. Wilson, R. S. Care, I. R. Peake, J. T. Reilly, Identification of novel FLT-3 Asp835 mutations in adult acute myeloid leukaemia. British Journal of Haematology. ,vol. 113, pp. 983- 988 ,(2001) , 10.1046/J.1365-2141.2001.02850.X

Ajeeta Dash, D.Gary Gilliland, Molecular genetics of acute myeloid leukaemia. Best Practice & Research Clinical Haematology. ,vol. 14, pp. 49- 64 ,(2001) , 10.1053/BEHA.2000.0115

Jan Cools, Daniel J. DeAngelo, Jason Gotlib, Elizabeth H. Stover, Robert D. Legare, Jorges Cortes, Jeffrey Kutok, Jennifer Clark, Ilene Galinsky, James D. Griffin, Nicholas C.P. Cross, Ayalew Tefferi, James Malone, Rafeul Alam, Stanley L. Schrier, Janet Schmid, Michal Rose, Peter Vandenberghe, Gregor Verhoef, Marc Boogaerts, Iwona Wlodarska, Hagop Kantarjian, Peter Marynen, Steven E. Coutre, Richard Stone, D. Gary Gilliland, A Tyrosine Kinase Created by Fusion of thePDGFRAandFIP1L1Genes as a Therapeutic Target of Imatinib in Idiopathic Hypereosinophilic Syndrome New England Journal of Medicine. ,vol. 348, pp. 1201- 1214 ,(2003) , 10.1056/NEJMOA025217

H. Nagata, A. S. Worobec, C. K. Oh, B. A. Chowdhury, S. Tannenbaum, Y. Suzuki, D. D. Metcalfe, Identification of a point mutation in the catalytic domain of the protooncogene c-kit in peripheral blood mononuclear cells of patients who have mastocytosis with an associated hematologic disorder Proceedings of the National Academy of Sciences of the United States of America. ,vol. 92, pp. 10560- 10564 ,(1995) , 10.1073/PNAS.92.23.10560