The emerging complexity of gene fusions in cancer
作者： Fredrik Mertens , Bertil Johansson , Thoas Fioretos , Felix Mitelman
DOI: 10.1038/NRC3947
关键词: Fusion gene 、 Carcinogenesis 、 Regulation of gene expression 、 Biology 、 Genetics 、 Mutation 、 DNA sequencing 、 Fusion protein 、 Gene 、 Gene regulatory network 、 Cancer research 、 Oncology
摘要: … of gene fusion and the tumour phenotype makes gene fusions ideal for diagnostic purposes, enabling … In addition, many gene fusions add important information for risk stratification, and …
nature.com
core.ac.uk
sci-hub.se 参考文章(174)
Eugen C. Minca, Bryce P. Portier, Zhen Wang, Christopher Lanigan, Carol F. Farver, Yan Feng, Patrick C. Ma, Valeria A. Arrossi, Nathan A. Pennell, Raymond R. Tubbs, ALK Status Testing in Non–Small Cell Lung Carcinoma: Correlation Between Ultrasensitive IHC and FISH The Journal of Molecular Diagnostics. ,vol. 15, pp. 341- 346 ,(2013) , 10.1016/J.JMOLDX.2013.01.004
P. B. Sinclair, E. P. Nacheva, M. Leversha, N. Telford, J. Chang, A. Reid, A. Bench, K. Champion, B. Huntly, A. R. Green, Large deletions at the t(9;22) breakpoint are common and may identify a poor-prognosis subgroup of patients with chronic myeloid leukemia. Blood. ,vol. 95, pp. 738- 743 ,(2000) , 10.1182/BLOOD.V95.3.738.003K21_738_743
Cancer Genome Atlas Research Network, None, Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia The New England Journal of Medicine. ,vol. 368, pp. 2059- 2074 ,(2013) , 10.1056/NEJMOA1301689
R. Berger, O. Bernard, C.-J. Larsen, V. Della Valle, D. Duro, T. Leblanc, Inactivation of the P16INK4/MTS1 Gene by a Chromosome Translocation t(9;14)(p21–22;q11) in an Acute Lymphoblastic Leukemia of B-Cell Type Cancer Research. ,vol. 56, pp. 848- 854 ,(1996)
P. C. Nowell, A minute chromosome in human chronic granulocytic leukemia Science. ,vol. 132, pp. 1497- ,(1960)
Hun J. Lee, James E. Thompson, Eunice S. Wang, Meir Wetzler, Philadelphia chromosome-positive acute lymphoblastic leukemia Cancer. ,vol. 117, pp. 1583- 1594 ,(2011) , 10.1002/CNCR.25690
F. Sanger, G. M. Air, B. G. Barrell, N. L. Brown, A. R. Coulson, J. C. Fiddes, C. A. Hutchison, P. M. Slocombe, M. Smith, Nucleotide sequence of bacteriophage φX174 DNA Nature. ,vol. 265, pp. 687- 695 ,(1977) , 10.1038/265687A0
Avery A. Sandberg, The chromosomes and causation of human cancer and leukemia. Cancer Research. ,vol. 26, pp. 2064- 2081 ,(1966)
JC Grimaldi, TC Meeker, The t(5;14) chromosomal translocation in a case of acute lymphocytic leukemia joins the interleukin-3 gene to the immunoglobulin heavy chain gene. Blood. ,vol. 73, pp. 2081- 2085 ,(1989) , 10.1182/BLOOD.V73.8.2081.2081
Theodor Boveri, Zur Frage der Entstehung maligner Tumoren G. Fischer. ,(1914)