Preparation method of degradable intravascular stent

作者: Quan Chunlan , Jin Zhongen , Zhang Fan

DOI:

关键词: ChitosanFibroinFreeze-dryingPolylactic acidBiomedical engineeringStentMaterials scienceDistilled waterStarchComposite number

摘要: The invention discloses a preparation method of degradable intravascular stent. comprises the steps firstly weighing polylactic acid fibers, collagen, silk fibroin, N-hydroxysuccinimide, oyster shell powder, chitosan, calcium sulfate hemihydrates, acetaminophen, ethanol, starch and distilled water in parts by weight, mixing, heating, stirring for reflux, after reflux is finished, cooling to room temperature so as obtain mixed solution, carrying out electrostatic spinning on collecting composite soaking fibers into taking out, freeze drying, degradation time stent material provided reaches 68-72 days, rate increased; blood compatibility good, adverse reaction such thrombus can be reduced; fracture strain resistance strong, thickness further decreased, circulation application micromolecule vessels are promoted. relatively safe, reliable effective use has good prospects.

参考文章(5)
Zhou Shaoxiong, Li Qiang, Bian Huijuan, Liang Xinjie, Yan Xinhao, Li Yubao, Cai Chenshui, Qin Yusheng, Wang Xianhong, Biodegradable medicament-loaded polymer scaffold and preparation method thereof ,(2014)