Spatial properties of nociceptor sensitization following heat injury of the skin

作者: Johann G. Thalhammer , Robert H. LaMotte

DOI: 10.1016/0006-8993(82)90364-X

关键词: Heat injuryReceptive fieldHeat sensitizationHeat stimulusAxonMedicineNeuroscienceNociceptorSensitizationDevelopmental biologyGeneral NeuroscienceMolecular biologyClinical neurology

摘要: A brief noxious heat stimulus applied to half of the receptive field each cutaneous nociceptor resulted in most cases enhanced responsiveness that subsequent stimuli (sensitization). No change was observed other field, indicating effects sensitization did not spread from site injury. In certain instances, area increased, but enlargement occurred only within The latter suggests existence outlying terminal endings parent axon are normally unresponsive non-injurious mechanical or become responsive these following

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