MK-801-induced impairments on the trial-unique, delayed nonmatching-to-location task in rats: effects of acute sodium nitroprusside.
作者： Jessica L. Hurtubise , Wendie N. Marks , Don A. Davies , Jillian K. Catton , Glen B. Baker
DOI: 10.1007/S00213-016-4451-2
关键词: Psychology 、 Vasodilator agents 、 Pattern separation 、 Pharmacology toxicology 、 Cognitive Symptoms 、 Anesthesia 、 Working memory 、 Schizophrenia 、 Sodium nitroprusside 、 NMDA receptor
摘要: Rationale The cognitive symptoms observed in schizophrenia are not consistently alleviated by conventional antipsychotics. Following a recent pilot study, sodium nitroprusside (SNP) has been identified as promising adjunct treatment to reduce the working memory impairments experienced patients.
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