Elevated copper in urine of Bangladeshi ethnic group living in the United Kingdom

摘要: Inductively Coupled Plasma – Mass Spectroscopy (ICP-MS) was used to monitor urinary selenium, copper and zinc in a group of Bangladeshi (n = 54), Indian 25), Pakistani 21), White Caucasian 23) volunteers living the UK. The most striking findings were far higher levels (P < 0.001) (median: 30.2 μg Cu/l) compared other ethnicities (15.6 Cu/l, Pakistani; 14.8 Indian; 10.5 Caucasians) reference values reported for UK population. Although no significant difference found Zn 0.22; medians: 430 Zn/l Bangladeshis, 377 Pakistani, 350 Caucasians, 355 Indians), significantly Cu:Zn ratio Bangladeshis. Urinary Se Bangladeshis (17.6 Se/l) Indians (13.8 (4.1 Se/l), although selenium generally within Exposure via ethnic food consumption or altered metabolism may contribute Cu group. Previous studies have correlated high serum cardiovascular diseases (CVD), liver cirrhosis, chronic hepatitis hepatocellular carcinoma (HCC). than average mortality from HCC disproportionately incidence CVD. detected therefore reflect early onset disease process, ultimately result these conditions members community.