Antifungal Immunological Defenses in Newborns
作者： Christina Michalski , Bernard Kan , Pascal M. Lavoie
关键词: Antifungal 、 Opportunistic pathogen 、 Biology 、 Context (language use) 、 Immunology 、 Immune system 、 Microbiome
摘要: Newborns are prone to fungal infections, largely due Candida species. The immunological basis for this vulnerability is not yet fully understood. However, useful insights can be gained from the knowledge of maturation immune pathways during ontogeny, particularly when placed in context with how rare genetic mutations humans predispose diseases. In article, we review these most current data on functions human newborns, highlighting relevant response Candida. While discussing data, propose a framework why deficiencies make newborns vulnerable opportunistic pathogen.
frontiersin.org
core.ac.uk
sci-hub.se 参考文章(125)
C. Chan, L. Bode, J. Kim, Galectin-3 binding protein in human preterm infant umbilical cord plasma. Journal of neonatal-perinatal medicine. ,vol. 8, pp. 99- 104 ,(2015) , 10.3233/NPM-15814055
Sophie Cypowyj, Capucine Picard, László Maródi, Jean‐Laurent Casanova, Anne Puel, None, Immunity to infection in IL-17-deficient mice and humans. European Journal of Immunology. ,vol. 42, pp. 2246- 2254 ,(2012) , 10.1002/EJI.201242605
M. Demmert, K. Faust, M. K. Bohlmann, B. Tröger, W. Göpel, E. Herting, C. Härtel, Galectin-3 in cord blood of term and preterm infants. Clinical and Experimental Immunology. ,vol. 167, pp. 246- 251 ,(2012) , 10.1111/J.1365-2249.2011.04509.X
Jonathan P Richardson, David L Moyes, Adaptive immune responses to Candida albicans infection Virulence. ,vol. 6, pp. 327- 337 ,(2015) , 10.1080/21505594.2015.1004977
Elisa C. Pinhat, Mayla G. S. Borba, Marina L. Ferreira, Marilisa A. Ferreira, Rafaela K. Fernandes, Stephanie K. Nicolaou, Cristina T. Okamoto, Carlos F. O. Neto, Fungal colonization in newborn babies of very low birth weight: a cohort study. Jornal De Pediatria. ,vol. 88, pp. 211- 216 ,(2012) , 10.2223/JPED.2192
Shih-Chin Cheng, Tom Sprong, Leo A.B. Joosten, Jos W. M. van der Meer, Bart-Jan Kullberg, Bernhard Hube, Lone Schejbel, Peter Garred, Marcel van Deuren, Mihai G. Netea, Complement plays a central role in Candida albicans-induced cytokine production by human PBMCs European Journal of Immunology. ,vol. 42, pp. 993- 1004 ,(2012) , 10.1002/EJI.201142057
Ashish A Sharma, Roger Jen, Bernard Kan, Abhinav Sharma, Elizabeth Marchant, Anthony Tang, Izabelle Gadawski, Christof Senger, Amanda Skoll, Stuart E Turvey, Laura M Sly, Hélène CF Côté, Pascal M Lavoie, None, Impaired NLRP3 inflammasome activity during fetal development regulates IL-1β production in human monocytes. European Journal of Immunology. ,vol. 45, pp. 238- 249 ,(2015) , 10.1002/EJI.201444707
Fayyaz S. Sutterwala, Sophie Joly, Ning Ma, Jeffrey J. Sadler, David R. Soll, Suzanne L. Cassel, Cutting Edge: Candida albicans Hyphae Formation Triggers Activation of the Nlrp3 Inflammasome Journal of Immunology. ,vol. 183, pp. 3578- 3581 ,(2009) , 10.4049/JIMMUNOL.0901323
Satoshi Okada, Janet G Markle, Elissa K Deenick, Federico Mele, Dina Averbuch, Macarena Lagos, Mohammed Alzahrani, Saleh Al-Muhsen, Rabih Halwani, Cindy S Ma, Natalie Wong, Claire Soudais, Lauren A Henderson, Hiyam Marzouqa, Jamal Shamma, Marcela Gonzalez, Rubén Martinez-Barricarte, Chizuru Okada, Danielle T Avery, Daniela Latorre, Caroline Deswarte, Fabienne Jabot-Hanin, Egidio Torrado, Jeffrey Fountain, Aziz Belkadi, Yuval Itan, Bertrand Boisson, Mélanie Migaud, Cecilia S Lindestam Arlehamn, Alessandro Sette, Sylvain Breton, James McCluskey, Jamie Rossjohn, Jean-Pierre de Villartay, Despina Moshous, Sophie Hambleton, Sylvain Latour, Peter D Arkwright, Capucine Picard, Olivier Lantz, Dan Engelhard, Masao Kobayashi, Laurent Abel, Andrea M Cooper, Luigi D Notarangelo, Stéphanie Boisson-Dupuis, Anne Puel, Federica Sallusto, Jacinta Bustamante, Stuart G Tangye, Jean-Laurent Casanova, None, Impairment of immunity to Candida and Mycobacterium in humans with bi-allelic RORC mutations Science. ,vol. 349, pp. 606- 613 ,(2015) , 10.1126/SCIENCE.AAA4282
Jiahui Chen, Xiaodan Yu, Yijun Zhou, Yongjun Zhang, Jianxing Zhu, Lijuan Xie, Jihong Qian, Qingnan Yang, Hongping Xia, Tianwen Zhu, Yonghong Zhang, Yan Chen, Dongying Zhao, Zhenjuan He, Integrated measures for prevention of invasive Candida infections in preterm infants in a Chinese neonatal intensive care unit American Journal of Infection Control. ,vol. 43, pp. 1321- 1325 ,(2015) , 10.1016/J.AJIC.2015.07.011