The potential role of telocytes in Tissue Engineering and Regenerative Medicine

摘要: Despite recent advances in surgery, medicine and anaesthesiology as well the development of microsurgical tissue transplantation, wear out body parts remains a problem, organ shortage does not allow to allocate enough donor organs for patients with vital diseases conditions. The idea create spare or from own cells by combining engineering approaches cellular molecular th purpose Tissue Engineering (TE) was fascinating when popularized early 1990ies. However clinically success limited, mainly because lack rapid vascularization large scale TE replacement constructs useful clinical purposes. utilize cytokines aid human organism gradually restoring lost functions has drawn attention wider field Regenerative Medicine (RM). Stem putative stem cells, such recently discovered meanwhile described interstitial Telocytes, which are comprised extremely long thin prolongations named telopodes, may become active players regenerative process. This article highlights principles RM potential role Telocytes regard regeneration.