Prevalence, incidence, and severity of hand eczema in the general population - A systematic review and meta-analysis.

作者: Jacob P Thyssen , Jeanne D Johansen , Anne B Simonsen , Anna S Quaade , Anne-Sofie Halling

DOI: 10.1111/COD.13804

关键词: PopulationPrevalenceMeta-analysisIncidence (epidemiology)Hand eczemaEpidemiologyDemographyMedicineConfidence intervalAtopic dermatitis

摘要: Accurate assessments of the burden hand eczema (HE) in general population are important for public awareness and intervention. The aim this systematic review meta-analysis was to provide updated estimates prevalence incidence, alongside additional epidemiological endpoints on HE population. PubMed, Embase Web Science were searched studies reporting and/or incidence Proportion meta-analyses performed calculate pooled prevalence, severity, proportion individuals with a history atopic dermatitis. Sixty-six included quantitative analysis encompassing 568 100 individuals. lifetime, 1-year, point 14.5% (95% confidence interval [CI]: 12.6-16.5), 9.1% CI: 8.4-9.8) 4.0% 2.6-5.7), respectively. rate 7.3 cases/1000 person-years 5.4-9.5). occurrence 1.5-2 times higher females than males. More one third suffered from moderate/severe disease around had recurrent, long-lasting an average age at onset early- mid-twenties. In conclusion; is highly prevalent carries significant risk long-term or chronic disease.

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