Hemorrhagic complications of long-term anticoagulant therapy for ischemic cerebral vascular disease.

摘要: The main complication of anticoagulant therapy is bleeding. Although the use long-term oral anticoagulants in patients with transient cerebral ischemia and/or minor stroke controversial, are still used some instances. We have carried out a literature review risk hemorrhage during cerebrovascular disease to determine rate bleeding and clinical laboratory factors which predispose was substantial major episodes ranging from 2% 22% per year fatal bleeds 9% year. Only hypertension emerged as an identifiable factor its presence increased relative more than two fold. Major almost always intracranial, possibly because associated or se. could not detect relationship between intensity therapy, although occurred frequently even only moderately intense therapy. net gain loss efficacy treating examined it concluded that order for such treatment be beneficial, reduction 50% rate, less required. Since death unlikely likely 2%, present evidence does support stroke.