Relation between exhaled carbon monoxide levels and clinical severity of asthma

摘要: Background Carbon monoxide (CO) can be detected in exhaled air and is increased asthmatic patients not treated with corticosteroids. However, it uncertain whether CO related to severity of asthma. Objective methods To study asthma clinical courses, concentrations were measured on a monitor by vital capacity manoeuvre 20 mild asthmatics inhaled β2-agonists alone, moderate corticosteroids, 15 stable high dose corticosteroids oral once month over 1 years. Exhaled also 16 unstable severe who visited the hospital every 7 or 14 days for treatment Results The mean values year 6.7 ± 9.5 p.p.m. (n = 31, SD) significantly higher than those non-smoking control subjects (1.2 0.9 p.p.m., n 20, P 0.20). There was significant relationship between forced expiratory volume one second all patients. Conclusion These findings suggest that may relate measurements useful means monitoring airway inflammation