Quantum magnetic resonance imaging diagnostics of human brain disorders

作者: Madan Kaila , Rakhi Kaila

DOI: 10.1016/B978-0-12-384711-9.00003-8

关键词: Restricted DiffusionNuclear magnetic resonancePhase (waves)Magnetic field gradientQuantumChemistrySignalDiffusion (business)Human brainMagnetic resonance imaging

摘要: The signal in magnetic resonance imaging MRI sequences depends on chemical composition of tissues; cellular organization and metabolism are little relevance. Diffusion-weighted images (DWI) is designed to evaluate diffusion movements the molecules a spatial axis. These incoherent microscopic molecular cause loss phase protons reduce intensity. Diffusion may be evaluated different axis at time/space scales, depending direction, timing, strength applied field gradients. Signal simply converted into an image or further elaborated obtain quantitative map ADC. A region restricted given will appear hyperintense DWI hypointense ADC maps. tissues capillary flow intracellular requiring active metabolism. In addition proton spectroscopy (PMRS) provides useful information, complementing that gained through MRI, with regard cell membrane proliferation, neuronal damage, energy metabolism, necrotic transformation brain tumor tissues. One needs able interpret both data accurately derive information about location, edema, mass effect, calcification, cyst formation, visualization, contrast enhancement, patient's age clinical presentation.

参考文章(66)
Elizabeth Bullitt, Donglin Zeng, Guido Gerig, Stephen Aylward, Sarang Joshi, J. Keith Smith, Weili Lin, Matthew G. Ewend, Vessel Tortuosity and Brain Tumor Malignancy Academic Radiology. ,vol. 12, pp. 1232- 1240 ,(2005) , 10.1016/J.ACRA.2005.05.027
Stephen W. Provencher, Automatic quantitation of localized in vivo 1H spectra with LCModel NMR in Biomedicine. ,vol. 14, pp. 260- 264 ,(2001) , 10.1002/NBM.698
Ulrike Dydak, Markus Weiger, Klaas P. Pruessmann, Dieter Meier, Peter Boesiger, Sensitivity-encoded spectroscopic imaging. Magnetic Resonance in Medicine. ,vol. 46, pp. 713- 722 ,(2001) , 10.1002/MRM.1250
R. Kreis, Quantitative localized 1H MR spectroscopy for clinical use Progress in Nuclear Magnetic Resonance Spectroscopy. ,vol. 31, pp. 155- 195 ,(1997) , 10.1016/S0079-6565(97)00014-9
Andrew A. Maudsley, G. B. Matson, J. W. Hugg, M. W. Weiner, Reduced phase encoding in spectroscopic imaging. Magnetic Resonance in Medicine. ,vol. 31, pp. 645- 651 ,(1994) , 10.1002/MRM.1910310610
H Lanfermann, H Kugel, W Heindel, K Herholz, W D Heiss, K Lackner, Metabolic changes in acute and subacute cerebral infarctions: findings at proton MR spectroscopic imaging. Radiology. ,vol. 196, pp. 203- 210 ,(1995) , 10.1148/RADIOLOGY.196.1.7784568
N. Salamon, N. Sicotte, J. Alger, D. Shattuck, S. Perlman, U. Sinha, H. Schultze-Haakh, G. Salamon, Analysis of the brain-stem white-matter tracts with diffusion tensor imaging. Neuroradiology. ,vol. 47, pp. 895- 902 ,(2005) , 10.1007/S00234-005-1439-8
S.A. Smith, T.O. Levante, B.H. Meier, R.R. Ernst, Computer Simulations in Magnetic Resonance. An Object-Oriented Programming Approach Journal of Magnetic Resonance, Series A. ,vol. 106, pp. 75- 105 ,(1994) , 10.1006/JMRA.1994.1008
Alex MacKay, Cornelia Laule, Irene Vavasour, Thorarin Bjarnason, Shannon Kolind, Burkhard Mädler, Insights into brain microstructure from the T2 distribution Magnetic Resonance Imaging. ,vol. 24, pp. 515- 525 ,(2006) , 10.1016/J.MRI.2005.12.037
Tamer S. Ibrahim, Chad Mitchell, Roney Abraham, Petra Schmalbrock, In-depth study of the electromagnetics of ultrahigh-field MRI NMR in Biomedicine. ,vol. 20, pp. 58- 68 ,(2007) , 10.1002/NBM.1094