Method of screening for melanoma by detecting an increase in cyclin D1
作者： Boris Bastian , Daniel Pinkel
DOI:
关键词: Chromosomal region 、 Polynucleotide 、 Melanoma 、 Molecular biology 、 Nucleic acid 、 Biology 、 Cyclin D1
摘要: The present invention provides methods of screening for the presence premalignant melanocytes in a sample from patient. comprise contacting nucleic acid biological patient with probe which binds selectively to target polynucleotide sequence on chromosomal region is amplified melanoma cells.
lens.org 参考文章(12)
Boris Bastian, Daniel Pinkel, Detection of premalignant melanocytes ,(1999)
T. J. Hudson, K. R. Loughlin, J. A. Fletcher, A. A. Renshaw, S. F. Huang, S. Xiao, Fluorescence in situ hybridization evaluation of chromosome deletion patterns in prostate cancer. American Journal of Pathology. ,vol. 149, pp. 1565- 1573 ,(1996)
Philip E. LeBoit, Eva-Bettina Bröcker, Boris C. Bastian, Henning Hamm, Dan Pinkel, Chromosomal Gains and Losses in Primary Cutaneous Melanomas Detected by Comparative Genomic Hybridization Cancer Research. ,vol. 58, pp. 2170- 2175 ,(1998)
Jia Xu, Tina Tyan, Edward Cedrone, Niramol Savaraj, Nancy Wang, Detection of 11q13 amplification as the origin of a homogeneously staining region in small cell lung cancer by chromosome microdissection. Genes, Chromosomes and Cancer. ,vol. 17, pp. 172- 178 ,(1996) , 10.1002/(SICI)1098-2264(199611)17:3<172::AID-GCC5>3.0.CO;2-1
A Kallioniemi, O. Kallioniemi, D Sudar, D Rutovitz, J. Gray, F Waldman, D Pinkel, Comparative Genomic Hybridization for Molecular Cytogenetic Analysis of Solid Tumors Science. ,vol. 258, pp. 818- 821 ,(1992) , 10.1126/SCIENCE.1359641
Phyllis A. Wingo, Lynn A.�G. Ries, Harry M. Rosenberg, Daniel S. Miller, Brenda K. Edwards, Cancer incidence and mortality, 1973-1995: a report card for the U.S. Cancer. ,vol. 82, pp. 1197- 1207 ,(1998) , 10.1002/(SICI)1097-0142(19980315)82:6<1197::AID-CNCR26>3.0.CO;2-0
P.J Heenan, A centimeter there, a centimeter there: Does it matter? Journal of the American Academy of Dermatology. ,vol. 35, pp. 281- 282 ,(1996) , 10.1016/S0190-9622(96)90357-6
Tetsuro Nagasaka, Raymond Lai, L. Jeffrey Medeiros, Russell K. Brynes, Althea McCourty, Tomoko Harada, Maruf Saddik, Cyclin D1 overexpression in Spitz nevi: an immunohistochemical study. American Journal of Dermatopathology. ,vol. 21, pp. 115- 120 ,(1999) , 10.1097/00000372-199904000-00001
Yutaka Mishima, T. Nakanishi, Acral lentiginous melanoma and its precursor—heterogeneity of palmo-plantar melanomas Pathology. ,vol. 17, pp. 258- 265 ,(1985) , 10.3109/00313028509063764
Daniel Pinkel, Joe W. Gray, Donna Albertson, Comparative fluorescence hybridization to nucleic acid arrays ,(1995)