Gut-innervating nociceptor neurons protect against enteric infection by modulating the microbiota and Peyer’s patch microfold cells
作者： Nicole Y Lai , Melissa A Musser , Felipe A Pinho-Ribeiro , Pankaj Baral , Pingchuan Ma
DOI: 10.1101/580555
关键词: Secretion 、 TRPV1 、 Biology 、 Nociceptor 、 Cell biology 、 Gut flora 、 Calcitonin gene-related peptide 、 Colonisation resistance 、 Peyer's patch 、 Microfold cell
摘要: … We tested the possibility that CGRP could directly inhibit the differentiation of M cells using … increasing doses of RTX (30, 70, and 100 ug/kg on consecutive days) dissolved in 2% DMSO/…
sci-hub.st 参考文章(140)
Stefano Evangelista, Capsaicin receptor as target of calcitonin gene-related peptide in the gut. Progress in drug research. ,vol. 68, pp. 259- 276 ,(2014) , 10.1007/978-3-0348-0828-6_10
Ifor R. Williams, Robert L. Owen, M Cells: Specialized Antigen Sampling Cells in the Follicle-Associated Epithelium Mucosal Immunology (Fourth Edition). pp. 211- 229 ,(2015) , 10.1016/B978-0-12-415847-4.00013-6
Justin Kuczynski, Jesse Stombaugh, William Anton Walters, Antonio González, J. Gregory Caporaso, Rob Knight, Using QIIME to analyze 16S rRNA gene sequences from Microbial Communities Current protocols in human genetics. ,vol. 36, ,(2011) , 10.1002/0471250953.BI1007S36
Werend Boesmans, Grzegorz Owsianik, Jan Tack, Thomas Voets, Pieter Vanden Berghe, TRP channels in neurogastroenterology: opportunities for therapeutic intervention British Journal of Pharmacology. ,vol. 162, pp. 18- 37 ,(2011) , 10.1111/J.1476-5381.2010.01009.X
Sebastien Talbot, Raja-Elie E Abdulnour, Patrick R Burkett, Seungkyu Lee, Shane JF Cronin, Maud A Pascal, Cedric Laedermann, Simmie L Foster, Johnathan V Tran, Nicole Lai, Isaac M Chiu, Nader Ghasemlou, Matthew DiBiase, David Roberson, Christian Von Hehn, Busranour Agac, Oliver Haworth, Hiroyuki Seki, Josef M Penninger, Vijay K Kuchroo, Bruce P Bean, Bruce D Levy, Clifford J Woolf, None, Silencing Nociceptor Neurons Reduces Allergic Airway Inflammation Neuron. ,vol. 87, pp. 341- 354 ,(2015) , 10.1016/J.NEURON.2015.06.007
John B. Furness, Trung V. Nguyen, Kulmira Nurgali, Yasutake Shimizu, The Enteric Nervous System and Its Extrinsic Connections Blackwell Publishing Ltd.. ,vol. 1, pp. 15- 39 ,(2009) , 10.1002/9781444303254.CH2
Meenakshi Rao, Bradlee D. Nelms, Lauren Dong, Viviana Salinas-Rios, Michael Rutlin, Michael D. Gershon, Gabriel Corfas, Enteric glia express proteolipid protein 1 and are a transcriptionally unique population of glia in the mammalian nervous system Glia. ,vol. 63, pp. 2040- 2057 ,(2015) , 10.1002/GLIA.22876
Andrés Vazquez-Torres, Jessica Jones-Carson, Andreas J. Bäumler, Stanley Falkow, Raphael Valdivia, William Brown, Mysan Le, Ruth Berggren, W. Tony Parks, Ferric C. Fang, Extraintestinal dissemination of Salmonella by CD18-expressing phagocytes Nature. ,vol. 401, pp. 804- 808 ,(1999) , 10.1038/44593
David Voehringer, Hong-Erh Liang, Richard M. Locksley, Homeostasis and effector function of lymphopenia-induced "memory-like" T cells in constitutively T cell-depleted mice. Journal of Immunology. ,vol. 180, pp. 4742- 4753 ,(2008) , 10.4049/JIMMUNOL.180.7.4742
Maria Rescigno, Matteo Urbano, Barbara Valzasina, Maura Francolini, Gianluca Rotta, Roberto Bonasio, Francesca Granucci, Jean-Pierre Kraehenbuhl, Paola Ricciardi-Castagnoli, Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria. Nature Immunology. ,vol. 2, pp. 361- 367 ,(2001) , 10.1038/86373