Allosteric mutant-selective fourth-generation EGFR inhibitors as an efficient combination therapeutic in the treatment of non-small cell lung carcinoma.

作者: Surya Kant Tripathi , Bijesh K. Biswal

DOI: 10.1016/J.DRUDIS.2021.02.005

关键词: CarcinomaT790MDrugAllosteric regulationEGFR inhibitorsCellCancer researchLungMutantMedicine

摘要: … compounds revealed that DDC-01-163 exhibited acceptable … Interestingly, DDC-01-163 treatment showed antiproliferative … The same study confirmed that the treatment of DDC-01-163 (…

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