Plasma fibronectin in asthmatic patients and its relation to asthma attack.

作者: Mine Harada , Kiyoshi Matsuo , Shinya Tada , Masashi Ohke , Mikiko Kataoka

DOI: 10.18926/AMO/32012

关键词: MedicineAsthmaBlood proteinsPlasma levelsEosinophil cationic proteinAllergic inflammationImmunologyFibronectinAsthma attackAsthmatic patient

摘要: This study investigated the relation between asthma attacks and levels of plasma fibronectin (FN) serum eosinophilic cationic protein (ECP) in patients with bronchial order to clarify role FN airway inflammation asthma. Plasma were significantly higher (P < 0.025) than healthy controls. They also 0.05) non-atopic asthmatics atopic asthmatics. Furthermore, was lower during attack non-attack stage 0.025), a significant increase noted who had more severe frequent attacks. Serum ECP 0.005). An after showed correlation decrease ECP. These observations clearly indicate that associated is closely related aggravation inflammation, reflects chronic inflammation. results suggest fluctuation may be one factors affecting allergic

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