Blood pressure treatment slows the progression of carotid stenosis in patients with isolated systolic hypertension.

作者: K Sutton-Tyrrell , S K Wolfson , L H Kuller

DOI: 10.1161/01.STR.25.1.44

关键词: ComplicationMedicineBlood flowCardiologyLumen (anatomy)SurgeryStenosisInternal medicineStrokeSystolic hypertensionBlood pressureVascular disease

摘要: The Systolic Hypertension in the Elderly Program (SHEP) was a randomized trial testing efficacy of treating systolic hypertension older adults. A significant reduction stroke risk observed among participants assigned to active treatment. Serial carotid duplex scans were performed on 129 at University Pittsburgh center, and rates progression regression stenosis observed.Changes blood flow velocity ratios used detect because they can be reliably measured their relation degree residual lumen is known. Progression required development 40% 50% diameter when not initially present or, if already present, further diameter. Regression absence or significantly less severe than that seen.Progression occurred 22% (28/129) 16% (8/49). ...

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