COMPOSITIONS AND METHODS RELATING TO MACROPHAGES AND/OR MONOCYTES WITH ADHERED PARTICLES

作者: Samir Mitragotri , Michael Andrew Evans , Charles Wyatt SHIELDS IV

DOI:

关键词: Payload (computing)ChemistryM2 phenotypeCell biology

摘要: Provided herein are polymeric particles and compositions (i.e., "backpacks") that can adhere to cells provide delivery of payload immunomodulatory agents those cells. For examples, the macrophages and/or monocytes release cytokines promote an M1 or M2 phenotype improve therapeutic efficacy

参考文章(2)
Bruce Panilaitis, David L. Kaplan, Jabier Gallego Llamas, Functionalization of biomaterials to control regeneration and inflammation responses ,(2012)
Albert Joseph Swiston, Michael F. Rubner, Darrell J. Irvine, Robert Edward Cohen, Synthetically functionalized living cells ,(2009)