Glucose and lipid assessment in patients with acute stroke

作者: Anthonia O Ogbera , Olajumoke O Oshinaike , Olusola Dada , Ayodeji Brodie-Mends , Chukwuma Ekpebegh

DOI: 10.1186/1755-7682-7-45

关键词: Lipid profileCross-sectional studyChi-square testDiabetes mellitusStrokeMedicineAcute strokeQuality of lifeIncidence (epidemiology)Pediatrics

摘要: Background: Stroke is a major health issue in Nigeria and it also common cause of emergency admissions. often results increased morbidity, mortality reduced quality life people thus affected. The risk factors for stroke include metabolic abnormalities such as dyslipidaemia diabetes mellitus (DM). stress an acute may present with hyperglycaemia persons without prior history DM, be pointer to or undiagnosed DM. Methodology: This was cross sectional study carried out over period one year teaching hospital Lagos, Nigeria. Patients admitted the within three days episode who met other inclusion criteria Study were consecutively recruited. Clinically relevant data documented biochemical assessments hospitalization. Tests lipid profile, glycosylated haemoglobin(HbA1c), blood glucose at presentation out. presence past abnormal profile noted. Students t test Chi square statistical tests employed. Results: A total 137 recruited which 107 (76%) defining ischaemic stroke. mean age range subjects 62.2 (11.7) 26–89 years respectively. classified according their glycaemic status into following categories viz; hyperglycaemia, euglycaemia, DM previously Stress occurred commonly fifth decade its incidence comparable between those cerebral haemorrhagic occurring elevated LDL-C low HDL. Conclusions: detection milieu window opportunity aggressive management this will improve outcome. Routine screening using haemoglobin uncover

参考文章(24)
Beatriz Marcheco, Juan de Jesús Llibre, Ana M. López, Carmen Moreno, Rudbeskia Porto, Adolfo Valhuerdi, Juan Carlos Llibre, Otman Fernández, Prevalence of stroke and associated risk factors in older adults in Havana City and Matanzas Provinces, Cuba (10/66 population-based study). MEDICC Review. ,vol. 12, pp. 20- 26 ,(2010)
Banumathy Srikant, Laxmikant Joshi, G Usha, K Sreedhar, Lipid profile in non-diabetic stroke--a study of 100 cases. Journal of Association of Physicians of India. ,vol. 58, pp. 547- 551 ,(2010)
Henri Darquennes, Marcel Kornitzer, Luc Berghmans, R. Payen, Raphaël Lagasse, Michèle Dramaix Wilmet, The World Health Organization MONICA Project (Monitoring trends and determinants in cardiovascular disease): A major international Collaboration Journal of Clinical Epidemiology. ,vol. 41, pp. 105- 114 ,(1988)
Takao Urabe, Hirotaka Watada, Yasuyuki Okuma, Ryota Tanaka, Yuji Ueno, Nobukazu Miyamoto, Yasutaka Tanaka, Nobutaka Hattori, Ryuzo Kawamori, Prevalence of Abnormal Glucose Metabolism and Insulin Resistance Among Subtypes of Ischemic Stroke in Japanese Patients Stroke. ,vol. 40, pp. 1289- 1295 ,(2009) , 10.1161/STROKEAHA.108.522557
S.A. Ogun, F.I. Ojini, B. Ogungbo, K.O. Kolapo, M.A. Danesi, Stroke in South West Nigeria A 10-Year Review Stroke. ,vol. 36, pp. 1120- 1122 ,(2005) , 10.1161/01.STR.0000166182.50840.31
John B. Kostis, The Importance of Managing Hypertension and Dyslipidemia to Decrease Cardiovascular Disease Cardiovascular Drugs and Therapy. ,vol. 21, pp. 297- 309 ,(2007) , 10.1007/S10557-007-6032-4
Kehinde O. Kolapo, Shamsideen A. Ogun, Mustapha A. Danesi, Bamidele Sanya Osalusi, Kayode A. Odusote, Validation Study of the Siriraj Stroke Score in African Nigerians and Evaluation of the Discriminant Values of Its Parameters A Preliminary Prospective CT Scan Study Stroke. ,vol. 37, pp. 1997- 2000 ,(2006) , 10.1161/01.STR.0000229893.02732.02
Dieter Mesotten, Greet Van den Berghe, Clinical Potential of Insulin Therapy in Critically Ill Patients Drugs. ,vol. 63, pp. 625- 636 ,(2003) , 10.2165/00003495-200363070-00001
Perttu J. Lindsberg, Risto O. Roine, Hyperglycemia in Acute Stroke Stroke. ,vol. 35, pp. 363- 364 ,(2004) , 10.1161/01.STR.0000115297.92132.84
Hariklia V. Dimitroula, Apostolos I. Hatzitolios, Haralambos I. Karvounis, The role of uric acid in stroke: the issue remains unresolved. The Neurologist. ,vol. 14, pp. 238- 242 ,(2008) , 10.1097/NRL.0B013E31815C666B