Chapter 5 Oxygen Sensing And The Hypoxic Ventilatory Response

作者: S.F. Perry , M.G. Jonz , K.M. Gilmour

DOI: 10.1016/S1546-5098(08)00005-8

关键词: Neuroepithelial cellAnesthesiaChemoreceptorHypoxic ventilatory responseDepolarizationBiophysicsBiologyAnaerobic exerciseNeurotransmitterRespirationRespiratory rate

摘要: The hypoxic ventilatory response is arguably the single most important physiological accompanying exposure of fish to lowered ambient P o 2 . Increases in ventilation volume, driven by changes breathing frequency and/or amplitude, serve raise arterial and hence may delay onset transition from aerobic anaerobic metabolism. In air‐breathing fish, consist increases aquatic aerial respiration. Ventilatory responses are initiated O chemoreceptors able detect water blood PO zebrafish, ‐sensing cells have been identified as neuroepithelial gill filament. hypoxia, undergo membrane depolarization owing an inhibition outwardly directed potassium currents that ultimately elcits calcium entry release neurotransmitter(s).

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