Vibrio cholerae cytolysin: structure-function mechanism of an atypical β-barrel pore-forming toxin.
作者： Anand Kumar Rai , Kausik Chattopadhyay
DOI: 10.1007/978-3-319-11280-0_7
关键词: Vibrio cholerae 、 Biophysics 、 Mode of action 、 Lipid bilayer 、 Protein structure 、 Cytolysin 、 Transmembrane protein 、 Context (language use) 、 Chemistry 、 Pore-forming toxin
摘要: β-Barrel pore-forming toxins (β-PFTs) represent a unique class of bacterial protein toxins. β-PFTs act by punching holes in the membrane lipid bilayer their target host cells. Generalized mechanism β-PFT mode action shows structural paradigm that involves formation transmembrane oligomeric β-barrel pores Vibrio cholerae cytolysin (VCC) is prominent member family, and it exhibits common features general. Structure–function VCC, however, highlights distinct are not commonly documented archetypical family members. In this review, we present brief description our current understanding regarding context its pore mechanism.
springer.com
sci-hub.se 参考文章(98)
W. Montfort, J.E. Villafranca, A.F. Monzingo, S.R. Ernst, B. Katzin, E. Rutenber, N.H. Xuong, R. Hamlin, J.D. Robertus, The Three-dimensional Structure of Ricin at 2.8 A* Journal of Biological Chemistry. ,vol. 262, pp. 5398- 5403 ,(1987) , 10.1016/S0021-9258(18)61201-3
Joseph E. Alouf, Bacterial Protein Toxins Methods of Molecular Biology. ,vol. 145, pp. 1- 26 ,(2000) , 10.1385/1-59259-052-7:1
Robert J. C. Gilbert, Cholesterol-dependent cytolysins. Advances in Experimental Medicine and Biology. ,vol. 677, pp. 56- 66 ,(2010) , 10.1007/978-1-4419-6327-7_5
F. Gisou van der Goot, Membrane-Damaging Toxins:Pore Formation American Society of Microbiology. pp. 189- 202 ,(2003) , 10.1128/9781555817893.CH13
J. E. Alouf, J. H. Freer, The comprehensive sourcebook of bacterial protein toxins Academic Press. ,(1999)
Karin Menzl, Elke Maier, Trinad Chakraborty, Roland Benz, HlyA Hemolysin of Vibrio Cholerae O1 Biotype El Tor FEBS Journal. ,vol. 240, pp. 646- 654 ,(1996) , 10.1111/J.1432-1033.1996.0646H.X
Kausik Chattopadhyay, Debasish Bhattacharyya, Kalyan K Banerjee, Vibrio cholerae hemolysin FEBS Journal. ,vol. 269, pp. 4351- 4358 ,(2002) , 10.1046/J.1432-1033.2002.03137.X
S L Goldberg, J R Murphy, Molecular cloning of the hemolysin determinant from Vibrio cholerae El Tor. Journal of Bacteriology. ,vol. 160, pp. 239- 244 ,(1984) , 10.1128/JB.160.1.239-244.1984
John H. Humphrey, Robert R. Dourmashkin, The lesions in cell membranes caused by complement. Advances in Immunology. ,vol. 11, pp. 75- 115 ,(1969) , 10.1016/S0065-2776(08)60478-2
Eric Gouaux, Rich Olson, Hirofumi Nariya, Kenji Yokota, Yoshiyuki Kamio, Crystal structure of staphylococcal LukF delineates conformational changes accompanying formation of a transmembrane channel. Nature Structural & Molecular Biology. ,vol. 6, pp. 134- 140 ,(1999) , 10.1038/5821