Characterization of nanoparticles: in vitro and in vivo
作者： Surendra Nimesh
关键词: Nanoparticle 、 Drug delivery 、 MTT assay 、 Chemistry 、 Confocal microscopy 、 Membrane 、 Nanotechnology 、 Cytotoxicity 、 In vivo 、 Flow cytometry
摘要: Efficacy of gene and drug delivery is dictated by the interaction nanoparticles with cell membranes. Since membranes are anionic in nature, cationic enhance Binding uptake have been characterized sophisticated microscopy flow cytometry techniques. depends on particles’ charge, size, shape type under investigation. Cytotoxicity has evaluated employing a multitude colorimetric assays exploiting either physical state or metabolic cells. Further, vivo characterization highly desirable deciphering various serum proteins. This chapter explores factors dictating different milieu technique employed.
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