Cationic amphiphiles with fatty acyl chain asymmetry of coconut oil deliver genes selectively to mouse lung.

作者: Voshavar Chandrashekhar , Marepally Srujan , Rairala Prabhakar , Rakesh C Reddy , Bojja Sreedhar

DOI: 10.1021/BC100537R

关键词: Acyl chainBiochemistryCationic polymerizationStereochemistryGene deliveryMouse LungCoconut oilAmphiphileChemistryGene

摘要: Recent structure−activity studies have revealed a dramatic influence of hydrophobic chain asymmetry in enhancing gene delivery efficacies synthetic cationic amphiphiles (Nantz, M. H. et al. Mol....

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