Effects of ageing on muscle O2 utilization and muscle oxygenation during the transition to moderate-intensity exercise.

作者: Darren S. DeLorey , Donald H. Paterson , John M. Kowalchuk

DOI: 10.1139/H07-121

关键词: PerfusionO2 consumptionMitochondrial enzymesUptake kineticsMicrocirculationAgeingIntensity (physics)Muscle oxygenationInternal medicineMedicineBiochemistryEndocrinology

摘要: At the onset of exercise, an increase in muscle and pulmonary O2 consumption is met by increases delivery extraction. Thus, study uptake kinetics reflects integrated response between convective diffusive systems metabolic machinery (i.e., mitochondrial enzyme activation provision acetyl groups to tricarboxcylic acid cycle) consumption. Pulmonary are slowed older adults compared with young previous studies suggest that slower may be result age-associated decline ability active muscles. However, inherent limitation understanding control limitations it methodologically difficult examine adaptation perfusion utilization microcirculation muscles th...

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