(Phenylpiperazinyl-butyl)oxindoles as selective 5-HT7 receptor antagonists.

作者: Balázs Volk , József Barkóczy , Endre Hegedus , Szabolcs Udvari , István Gacsályi

DOI: 10.1021/JM070279V

关键词: OxindoleLactamChemical synthesisSelectivityStereochemistryChemistry5-HT7 receptorBicyclic molecule5-HT receptorAromaticity

摘要: … ,6-tetrahydropyridines also proved to be 5-HT 7 receptor–… -ethyl-6-fluoro-1,3-dihydro-2H-indol-2-one (9e′) exhibited … We aimed at elaborating an efficient synthesis of new compounds …

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