Lactobacillus species as emerging pathogens in neutropenic patients

作者: C. Fruchart , A. Salah , C. Gray , E. Martin , A. Stamatoullas

DOI: 10.1007/BF01708560

关键词: ImmunologyVancomycinNeutropeniaLeukopeniaIntensive care unitInternal medicinePenicillinAntibacterial agentAntibioticsCeftazidimeMedicine

摘要: The intensive use of broad-spectrum antibiotics in the context prolonged and severe neutropenia has contributed to emergence unusual pathogens. Four new cases Lactobacillus infections-three septicemia one pneumonia-are reported. They occurred patients with acute leukemia who had chemotherapy-induced neutropenia. All were treated same care unit received antimicrobial prophylaxis which included a total bowel decontamination containing vancomycin. four combination intravenous ceftazidime vancomycin prior development infection. Improvement condition all was obtained treatment including penicillin concurrent recovery granulopoiesis.

参考文章(15)
Arnold S. Bayer, Anthony W. Chow, David Betts, Lucien B. Guze, Lactobacillemia—Report of nine cases The American Journal of Medicine. ,vol. 64, pp. 808- 813 ,(1978) , 10.1016/0002-9343(78)90521-1
M Green, K Barbadora, M Michaels, Recovery of vancomycin-resistant gram-positive cocci from pediatric liver transplant recipients. Journal of Clinical Microbiology. ,vol. 29, pp. 2503- 2506 ,(1991) , 10.1128/JCM.29.11.2503-2506.1991
M. Chomarat, D. Espinouse, Lactobacillus rhamnosus septicemia in patients with prolonged aplasia receiving ceftazidime-vancomycin European Journal of Clinical Microbiology & Infectious Diseases. ,vol. 10, pp. 44- 44 ,(1991) , 10.1007/BF01967099
Rosalind Maskell, Linda Pead, 4-Fluoroquinolones and Lactobacillus spp as emerging pathogens. The Lancet. ,vol. 339, pp. 929- 929 ,(1992) , 10.1016/0140-6736(92)90965-6
J. I. Sussman, E. J. Baron, S. M. Goldberg, M. H. Kaplan, R. A. Pizzarello, Clinical Manifestations and Therapy of Lactobacillus Endocarditis: Report of a Case and Review of the Literature Clinical Infectious Diseases. ,vol. 8, pp. 771- 776 ,(1986) , 10.1093/CLINIDS/8.5.771
R. Patel, F. R. Cockerill, M. K. Porayko, D. R. Osmon, D. M. Ilstrup, M. R. Keating, Lactobacillemia in Liver Transplant Patients Clinical Infectious Diseases. ,vol. 18, pp. 207- 212 ,(1994) , 10.1093/CLINIDS/18.2.207
J. K. Griffiths, J. S. Daly, R. A. Dodge, Two Cases of Endocarditis due to Lactobacillus Species: Antimicrobial Susceptibility, Review, and Discussion of Therapy Clinical Infectious Diseases. ,vol. 15, pp. 250- 255 ,(1992) , 10.1093/CLINIDS/15.2.250
S. Sriskandan, S. Lacey, L. Fischer, Isolation of vancomycin-resistant lactobacilli from three neutropenic patients with pneumonia. European Journal of Clinical Microbiology & Infectious Diseases. ,vol. 12, pp. 649- 650 ,(1993) , 10.1007/BF01973653
R.E. Holliman, G.P. Bone, Vancomycin resistance of clinical isolates of lactobacilli Journal of Infection. ,vol. 16, pp. 279- 283 ,(1988) , 10.1016/S0163-4453(88)97676-1
D. Tande, I. Yakoub Agha, L. Burette, C. Berthou, M.L. Abalain, C. Chastel, Septicémie à Lactobacillus casei var. rhamnosus : translocation chez une leucémique ? Medecine Et Maladies Infectieuses. ,vol. 22, pp. 493- 495 ,(1992) , 10.1016/S0399-077X(05)80285-9