Aging-associated oxidative stress leads to decrease in IAS tone via RhoA/ROCK downregulation

作者: Jagmohan Singh , Sumit Kumar , Chadalavada Vijay Krishna , Satish Rattan , None

DOI: 10.1152/AJPGI.00087.2014

关键词: Internal anal sphincterRHOAEndocrinologyInternal medicineDownregulation and upregulationTone (literature)Oxidative stressBiology

摘要: Internal anal sphincter (IAS) tone plays an important role in rectoanal incontinence (RI). IAS may be compromised during aging, leading to RI certain patients. We examined the influence of ...

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