The accuracy of late third-trimester antenatal screening for group B streptococcus in predicting colonization at delivery.

作者: Craig Towers , Pamela Rumney , Tamerou Asrat , Christine Preslicka , Mark Ghamsary

DOI: 10.1055/S-0030-1254237

关键词: Group BPregnancyPediatricsMedicinePrenatal diagnosisPredictive value of testsClinical trialObstetricsMicrobiological cultureConfidence intervalStreptococcus

摘要: We reevaluated the accuracy of antenatal group B streptococcal (GBS) culture results in predicting colonization at time delivery a general practice setting. Patients who had late third-trimester GBS cultures were prospectively identified. A repeat was performed when admitted labor using strict protocol and laboratory analysis. Sensitivity, specificity, positive negative predicative values calculated. In comparing office to intrapartum 1472 patients, sensitivity 51%, specificity 94%, predictive value 67%, 88%. The rate 15.4% significantly lower than 20.1% rate. There 144 patients (9.8%) false-negative results. Through survey, several aspects recommended procedures not followed. support previously reported high for this test. near 10% with significant difference between versus highly suggests that may be affected if specified are completely followed, including culturing technique, use transport medium, protocol.

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