Total synthesis of both (+)-compactin and (+)-mevinolin : a general strategy based on the use of a special titanium reagent for dicarbonyl coupling

作者: Derrick L. J. Clive , K. S. Keshava Murthy , Andrew G. H. Wee , J. Siva Prasad , Gil V. J. Da Silva

DOI: 10.1021/JA00164A024

关键词: Organic chemistryEnantiomerChemistryBicyclic moleculeTotal synthesisLactoneStereoselectivityReagentTitanium

摘要: A strategy is described for stereocontrolled synthesis of hypocholesterolemic compounds, (+)-compactin(+)-mevinolin

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