Oral delivery of modified transferrin fusion proteins
作者： Andrew Turner , Homayoun Sadeghi , Christopher P. Prior
DOI:
关键词: Transferrin 、 Glycosylation 、 Transferrin receptor 、 Chemistry 、 Fusion protein 、 Moiety 、 Biochemistry
摘要: Pharmaceutical compositions containing modified fusion proteins of transferrin and therapeutic or peptides with increased serum half-life stability are disclosed. Preferred include those so that the moiety exhibits no reduced glycosylation, but does exhibit binding to iron and/or receptor. Such may be administered orally.
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