Characterization of spirostanol glycosides and furostanol glycosides from anemarrhenae rhizoma as dual targeted inhibitors of 5-lipoxygenase and Cyclooxygenase-2 by employing a combination of affinity ultrafiltration and HPLC/MS

作者: Linlin Xie , David Yue-wei Lee , Ying Shang , Xiaotong Cao , Siqi Wang

DOI: 10.1016/J.PHYMED.2020.153284

关键词: In vivoHigh-performance liquid chromatographyIC50EnzymeUltrafiltration (renal)Arachidonate 5-lipoxygenaseGlycosideMass spectrometryChemistryChromatography

摘要: … -inflammatory components of the saponins from Anemarrhenae Rhizoma based on 5-LOX/… potential inhibitors from the saponins extract of Anemarrhenae Rhizoma (SEAR). To the best …

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