Pyridine ligands as promoters in Pd(II/0)-catalyzed C-H olefination reactions.
作者： Asako Kubota , Marion H. Emmert , Melanie S. Sanford
DOI: 10.1021/OL300281P
关键词: Promoter 、 Reaction rate 、 Catalysis 、 Site selectivity 、 Substrate (chemistry) 、 Medicinal chemistry 、 Pyridine ligand 、 Pyridine 、 Chemistry 、 Stereochemistry 、 Yield (chemistry)
摘要: Commercially available pyridine ligands can significantly enhance the rate, yield, substrate scope, and site selectivity of arene C–H olefination (Fujiwara–Moritani) reactions. The use a 1:1 ratio Pd/pyridine proved critical to maximize reaction rates yields.
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