作者: Jens Ricke , Peter Wust
DOI: 10.1016/J.SEMRADONC.2011.05.005
关键词: Hepatocellular carcinoma 、 Radiology 、 Cirrhosis 、 Catheter 、 Brachytherapy 、 Bile duct 、 Medicine 、 Radiation therapy 、 Percutaneous 、 Liver cancer
摘要: Limitations of thermal liver cancer ablation have led to the development percutaneous, catheter-based brachytherapy for treatment malignancies. Computed tomography (CT)-guided has been used treat primary and metastatic cancers, including very large tumors >10 cm. Cooling effects by adjacent blood vessels are not a concern in brachytherapy, method may be safely unsuitable that close hilum due relatively high radiation tolerance bile duct. CT scanning is dosimetry planning after catheter implantation also guide placement itself. Major complications, postinterventional bleeding, rare despite frequent application this technique salvage situation. Patients with cirrhosis an increased risk complications. Prospective trials CT-guided performed promising survival rates metastases hepatocellular carcinoma, respectively. In article, radiobiological technical properties appropriate patients treatment, prospective published date reviewed.