Immunodiagnostics and immunosensor design

作者: Vladimir Gubala , Reinhild Klein , Douglas M. Templeton , Michael Schwenk

DOI: 10.1515/PAC-2013-1027

关键词: ChemistryHuman healthImmunodiagnosticsAddictive drugsComputational biologyDisease markersMolecular biology

摘要: This work compiles information on the principles of diagnostic immunochemical methods and recent advances in this field. It presents an overview modern techniques for production diag- nostic antibodies, their modification with aim improving potency, different types detection systems, increasing applications human health that include specific disease markers, individualized diagnosis cancer subtypes, therapeutic addictive drugs, food residues, environmental contaminants. A special focus lies novel developments immu- nosensor techniques, promising approaches to miniaturized units associated microfluidic systems. The trends towards high-throughput multiplexed analysis, miniaturization tools are discussed. is also made evident progress last few years has largely relied chemical approaches.

参考文章(84)
Jens Hansen, Michael Rink, Markus Graefen, Shahrokh Shariat, Felix K.-H. Chun, Assays for Prostate Cancer Molecular Diagnosis & Therapy. ,vol. 17, pp. 1- 8 ,(2013) , 10.1007/S40291-013-0014-Y
Daniel J. Ehrlich, Brian K. McKenna, James G. Evans, Anna C. Belkina, Gerald V. Denis, David H. Sherr, Man Ching Cheung, Parallel imaging microfluidic cytometer. Methods in Cell Biology. ,vol. 102, pp. 49- 75 ,(2011) , 10.1016/B978-0-12-374912-3.00003-1
Cyril Fisher, Immunohistochemistry in diagnosis of soft tissue tumours Histopathology. ,vol. 58, pp. 1001- 1012 ,(2011) , 10.1111/J.1365-2559.2010.03707.X
Kevin J. Whaley, Josh Morton, Steve Hume, Ernie Hiatt, Barry Bratcher, Victor Klimyuk, Andrew Hiatt, Michael Pauly, Larry Zeitlin, Emerging Antibody-based Products Current Topics in Microbiology and Immunology. ,vol. 375, pp. 107- 126 ,(2012) , 10.1007/82_2012_240
Nicholas Gerard Byrne, David Geraint Owen, High throughput screen ,(1999)
Nicholas A Saunders, Application of nanomaterials to arrays for infectious disease diagnosis Nanomedicine: Nanotechnology, Biology and Medicine. ,vol. 6, pp. 271- 280 ,(2011) , 10.2217/NNM.10.161
Chun-Ping Jia, Xiao-Qin Zhong, Bao Hua, Mei-Ying Liu, Feng-Xiang Jing, Xin-Hui Lou, Shi-Hua Yao, Jia-Qing Xiang, Qing-Hui Jin, Jian-Long Zhao, Nano-ELISA for highly sensitive protein detection. Biosensors and Bioelectronics. ,vol. 24, pp. 2836- 2841 ,(2009) , 10.1016/J.BIOS.2009.02.024
Mingxing Liu, Huifang Li, Guoan Luo, Qingfei Liu, Yiming Wang, Pharmacokinetics and biodistribution of surface modification polymeric nanoparticles Archives of Pharmacal Research. ,vol. 31, pp. 547- 554 ,(2008) , 10.1007/S12272-001-1191-8
Robert Byrne, Fernando Benito-Lopez, Dermot Diamond, Materials science and the sensor revolution Materials Today. ,vol. 13, pp. 16- 23 ,(2010) , 10.1016/S1369-7021(10)70124-3