Indications for Surgical Resection in Low-Grade Pancreatic Neuroendocrine Tumors.
作者： Timothy L. Fitzgerald , Catalina Mosquera , Haily S. Vora , Nasreen A. Vohra , Emmanuel E. Zervos
DOI: 10.1177/000313481608200834
关键词: Gastroenterology 、 Neuroendocrine tumors 、 Medicine 、 Survival rate 、 Internal medicine 、 Increased risk 、 Node negative 、 Univariate analysis 、 Surgery 、 Surgical resection 、 Tumor size 、 Pancreatectomy
摘要: The role of surgical resection in low-grade pancreatic neuroendocrine tumors (P-NET) is unclear. patients diagnosed with P-NET from 1988 to 2012 were identified SEER. Five hundred and sixty-one met the inclusion criteria. A majority white (82.9%), node negative (69.9%). Univariate analysis revealed that tumor size ( 4 cm 40.3%; P 74.5%; = 0.0089), LNM (72.4% vs 82.9%; 0.0025), surgery (84.3% 47.5%; 2 (2-4 cm, 84.4% 26.0% at five years; 0.0003, >4 80.5% 49.5% showed an increased risk improved survival resection.
sci-hub.st 参考文章(32)
Kristin Gross, Jjais Richards, Ihab Lamzabi, Maria Mora Pinzon, Amanda Francescatti, Marc Brand, Shriram Jakate, Dana Hayden, Theodore Saclarides, Distribution of gastrointestinal neuroendocrine tumors: a changing paradigm. American Surgeon. ,vol. 81, pp. 221- 223 ,(2015) , 10.1177/000313481508100240
Jordan M Cloyd, George A Poultsides, Non-functional neuroendocrine tumors of the pancreas: Advances in diagnosis and management World Journal of Gastroenterology. ,vol. 21, pp. 9512- 9525 ,(2015) , 10.3748/WJG.V21.I32.9512
Timothy L. Fitzgerald, Samuel O. Dennis, Swapnil D. Kachare, Nasreen A. Vohra, Emmanuel E. Zervos, Increasing incidence of duodenal neuroendocrine tumors: Incidental discovery of indolent disease? Surgery. ,vol. 158, pp. 466- 471 ,(2015) , 10.1016/J.SURG.2015.03.042
Timothy L. Fitzgerald, Zach J. Hickner, Matthew Schmitz, Eric J. Kort, Changing incidence of pancreatic neoplasms: a 16-year review of statewide tumor registry. Pancreas. ,vol. 37, pp. 134- 138 ,(2008) , 10.1097/MPA.0B013E318163A329
Paul A. Toste, Brian E. Kadera, Sergei F. Tatishchev, David W. Dawson, Barbara M. Clerkin, Raman Muthusamy, Rabindra Watson, James S. Tomlinson, Oscar J. Hines, Howard A. Reber, Timothy R. Donahue, Nonfunctional pancreatic neuroendocrine tumors <2 cm on preoperative imaging are associated with a low incidence of nodal metastasis and an excellent overall survival. Journal of Gastrointestinal Surgery. ,vol. 17, pp. 2105- 2113 ,(2013) , 10.1007/S11605-013-2360-9
Dong Wook Kim, Hyoung Jung Kim, Kyung Won Kim, Jae Ho Byun, Ki Byung Song, Ji Hoon Kim, Seung-Mo Hong, Neuroendocrine neoplasms of the pancreas at dynamic enhanced CT: comparison between grade 3 neuroendocrine carcinoma and grade 1/2 neuroendocrine tumour. European Radiology. ,vol. 25, pp. 1375- 1383 ,(2015) , 10.1007/S00330-014-3532-Z
Lauren Gratian, John Pura, Michaela Dinan, Sanziana Roman, Shelby Reed, Julie Ann Sosa, Impact of extent of surgery on survival in patients with small nonfunctional pancreatic neuroendocrine tumors in the United States. Annals of Surgical Oncology. ,vol. 21, pp. 3515- 3521 ,(2014) , 10.1245/S10434-014-3769-4
Malcolm H. Squires, N. Volkan Adsay, David M. Schuster, Maria C. Russell, Kenneth Cardona, Keith A. Delman, Joshua H. Winer, Deniz Altinel, Juan M. Sarmiento, Bassel El-Rayes, Natalyn Hawk, Charles A. Staley, Shishir K. Maithel, David A. Kooby, Octreoscan Versus FDG-PET for Neuroendocrine Tumor Staging: A Biological Approach Annals of Surgical Oncology. ,vol. 22, pp. 2295- 2301 ,(2015) , 10.1245/S10434-015-4471-X
Sébastien Gaujoux, Alain Sauvanet, Stefano Partelli, Massimo Falconi, Philippe Ruszniewski, Comment on "predicting aggressive behavior in nonfunctioning pancreatic neuroendocrine". Surgery. ,vol. 155, pp. 582- 584 ,(2014) , 10.1016/J.SURG.2013.11.004
Yassar M. Hashim, Kathryn M. Trinkaus, David C. Linehan, Steven S. Strasberg, Ryan C. Fields, Dengfeng Cao, William G. Hawkins, Regional lymphadenectomy is indicated in the surgical treatment of pancreatic neuroendocrine tumors (PNETs). Annals of Surgery. ,vol. 259, pp. 197- 203 ,(2014) , 10.1097/SLA.0000000000000348