An integrative approach to improving the biocatalytic reactions of whole cells expressing recombinant enzymes.
作者： Deok-Kun Oh , Kyung-Chul Shin
DOI: 10.1007/S11274-021-03075-6
关键词: Biochemistry 、 Biotransformation 、 Environmentally friendly 、 Chemistry 、 Enzyme 、 Chemical synthesis 、 Whole cell 、 Recombinant DNA 、 Metabolic engineering 、 Protein engineering
摘要: Biotransformation is a selective, stereospecific, efficient, and environment friendly method, compared to chemical synthesis, feasible tool for industrial pharmaceutical applications. The design of biocatalysts using enzyme engineering metabolic tools has been widely reviewed. However, less importance given the biocatalytic reaction whole cells expressing recombinant enzymes. Along with remarkable development biotechnology tools, variety techniques have applied improve cell biotransformation. In this review, related are examined, reorganized, summarized via an integrative approach. Moreover, equilibrium-shifted biotransformation reviewed first time.
sci-hub.st 参考文章(139)
Ye Seop Park, Un Jong Choi, Nguyen Hoai Nam, Sang Jin Choi, Abdul Nasir, Sun-Gu Lee, Kyung Jin Kim, Gyoo Yeol Jung, Sangdun Choi, Jeung Yeop Shim, Sunghoon Park, Tae Hyeon Yoo, Engineering an aldehyde dehydrogenase toward its substrates, 3-hydroxypropanal and NAD+, for enhancing the production of 3-hydroxypropionic acid. Scientific Reports. ,vol. 7, pp. 17155- ,(2017) , 10.1038/S41598-017-15400-X
Martina Hestericová, Tillman Heinisch, Lur Alonso-Cotchico, Jean-Didier Maréchal, Pietro Vidossich, Thomas R. Ward, Directed Evolution of an Artificial Imine Reductase Angewandte Chemie. ,vol. 57, pp. 1863- 1868 ,(2018) , 10.1002/ANIE.201711016
Jung-Ung An, Yong-Seok Song, Kyoung-Rok Kim, Yoon-Joo Ko, Do-Young Yoon, Deok-Kun Oh, Biotransformation of polyunsaturated fatty acids to bioactive hepoxilins and trioxilins by microbial enzymes. Nature Communications. ,vol. 9, pp. 128- ,(2018) , 10.1038/S41467-017-02543-8
Hans Adrian Bunzel, Xavier Garrabou, Moritz Pott, Donald Hilvert, Speeding up enzyme discovery and engineering with ultrahigh-throughput methods. Current Opinion in Structural Biology. ,vol. 48, pp. 149- 156 ,(2018) , 10.1016/J.SBI.2017.12.010
Yan Li, Xiaoguang Xu, Rui Qu, Guoqiang Zhang, Muhammad Shahid Riaz Rajoka, Dongyan Shao, Chunmei Jiang, Junling Shi, Heterologous expression of Oenococcus oeni sHSP20 confers temperature stress tolerance in Escherichia coli. Cell Stress & Chaperones. ,vol. 23, pp. 653- 662 ,(2018) , 10.1007/S12192-018-0874-5
Larry E Taylor, Brandon C Knott, John O Baker, P Markus Alahuhta, Sarah E Hobdey, Jeffrey G Linger, Vladimir V Lunin, Antonella Amore, Venkataramanan Subramanian, Kara Podkaminer, Qi Xu, Todd A VanderWall, Logan A Schuster, Yogesh B Chaudhari, William S Adney, Michael F Crowley, Michael E Himmel, Stephen R Decker, Gregg T Beckham, None, Engineering enhanced cellobiohydrolase activity. Nature Communications. ,vol. 9, pp. 1186- 1186 ,(2018) , 10.1038/S41467-018-03501-8
Andrea M. Chánique, Loreto P. Parra, Protein Engineering for Nicotinamide Coenzyme Specificity in Oxidoreductases: Attempts and Challenges. Frontiers in Microbiology. ,vol. 9, pp. 194- 194 ,(2018) , 10.3389/FMICB.2018.00194
Junzhi Wang, Cheng Zheng, Yang Cao, Zhuotao Tan, Dong Liu, Zhuopei Cheng, Hanjie Ying, Huanqing Niu, Rational Design of an Efficient Halotolerant Enzymatic System for In Vitro One-Pot Synthesis of Cytidine Diphosphate Choline Biotechnology Journal. ,vol. 13, pp. 1700577- ,(2018) , 10.1002/BIOT.201700577
Kil Koang Kwon, Dae-Hee Lee, Su Jin Kim, Su-Lim Choi, Eugene Rha, Soo-Jin Yeom, Bindu Subhadra, Jinhyuk Lee, Ki Jun Jeong, Seung-Goo Lee, Evolution of enzymes with new specificity by high-throughput screening using DmpR-based genetic circuits and multiple flow cytometry rounds Scientific Reports. ,vol. 8, pp. 2659- 2659 ,(2018) , 10.1038/S41598-018-20943-8
Thi Khoa My Nguyen, Mi Ran Ki, Ryeo Gang Son, Seung Pil Pack, The NT11, a novel fusion tag for enhancing protein expression in Escherichia coli. Applied Microbiology and Biotechnology. ,vol. 103, pp. 2205- 2216 ,(2019) , 10.1007/S00253-018-09595-W