Taxadiene synthase structure and evolution of modular architecture in terpene biosynthesis

作者: Mustafa Köksal , Yinghua Jin , Robert M. Coates , Rodney Croteau , David W. Christianson

DOI: 10.1038/NATURE09628

关键词: IsomeraseTaxadiene synthaseTaxus brevifoliaStereochemistryDiterpeneATP synthaseChemistryLyaseCyclaseBiochemistryPeptide sequence

摘要: … life, the family of terpene or terpenoid natural products represents … The first committed step of Taxol biosynthesis in the Pacific … cyclase classes in the evolution of terpenoid biosynthesis. …

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