Chemical Structures of Plant Hydrolyzable Tannins Reveal Their in Vitro Activity against Egg Hatching and Motility ofHaemonchus contortusNematodes
作者： M. T. Engström , M. Karonen , J. R. Ahern , N. Baert , B. Payré
关键词: Hatching 、 Biochemistry 、 Biology 、 Polyphenol 、 Gallic acid 、 Nematode 、 Haemonchus contortus 、 Botany 、 Anthelmintic 、 Tannin 、 Hydrolyzable Tannin 、 General chemistry 、 General Agricultural and Biological Sciences
摘要: The use of synthetic drugs against gastrointestinal nematodes ruminants has led to a situation where resistance anthelmintics is widespread, and there an urgent need for alternative solutions parasite control. One promising approach polyphenol-rich bioactive plants in animal feeds as natural anthelmintics. In the present work, vitro activity series 33 hydrolyzable tannins (HTs) their hydrolysis product, gallic acid, egg hatching motility L1 L2 stage Haemonchus contortus larvae was studied. effect selected compounds on larval structure further studied by scanning electron microscopy. results indicated clear relationships between HT anthelmintic activity. While size, overall flexibility, types numbers functional groups, together with linkage monomeric HTs affected differently, optimal found pentagalloylglucose.
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