Сосудистые когнитивные нарушения при хронической болезни почек

摘要: Objective : to study the specific features of development cognitive impairments (CIs), role traditional cardiovascular risk factors and renal failure-induced in patients with Stages I–IV chronic kidney disease (CKD) assess an association CIs signs vascular wall remodeling them. Patients methods. Fifty-one aged 53±10 years CKD were examined. Among them, there 20 I–II CKD: a glomerular filtration rate (GFR) і60 ml/min/1.73 m 2 , lesion; III GFR <60–30 11 VI <30–15 .  Results discussion. more common III–IV than those I–II, as shown by scores mini-mental state examination (p<0.001), frontal assessment battery (p=0.001), regulatory function test (p<0.001). These tests showed that magnitude increased higher stage CKD. is independent predictor persons predialysis-stage lesion. found be related hyperhomocysteinemia, anemia, abdominal obesity, left ventricular hypertrophy, patient age. The atherosclerotic lesion carotid arteries indicators arterial stiffness also associated incidence CKD.  detection early allows one timely initiate adequate therapy aimed particularly at improving cerebral circulation, eliminating impact factors, slowing down remodeling. management tactics for must involve identification correction duplex scanning may used noninvasive method progression predialysis